Pill identification — FDA label match

U 420 Pill — Amitriptyline Hydrochloride 25 mg (Yellow, Round)

A yellow round tablet with the imprint U 420 matches the FDA label for Amitriptyline Hydrochloride 25 mg. Compare every detail below with your pill, and confirm with a pharmacist before relying on it.

ImprintU 420
Imprint partsU · 420 (the code is split across the pill — often one part per side)
Generic nameAmitriptyline Hydrochloride
Active ingredient(s)Amitriptyline Hydrochloride 25 mg
Strength25 mg
Dosage formTablet, Film Coated
ColourYellow
ShapeRound
Size6 mm
ScoreNo score
LabelerRemedyrepack Inc.
NDC examples70518-3641-0, 70518-3641-1, 70518-3641-2

What this medicine is

According to its FDA-approved label, Amitriptyline Hydrochloride is described as follows (reference information only — not advice about whether it is right for anyone):

For the relief of symptoms of depression. Endogenous depression is more likely to be alleviated than are other depressive states.

Equivalent pills — same medicine, different imprint

The pills below contain the same active ingredient at the same strength (Amitriptyline Hydrochloride 25 mg). Different makers stamp their own codes, so equivalent pills often look completely different. This is factual label information — it is not a suggestion to substitute one product for another; only a pharmacist or prescriber can advise on that.

31 Amitriptyline Hydrochloride 25 mg — Green · round · 6 mm
I2 Amitriptyline Hydrochloride 25 mg — Brown · round · 7 mmFull page in a later wave
2102 V Amitriptyline Hydrochloride 25 mg — Yellow · round · 6 mmFull page in a later wave
AP21 Amitriptyline Hydrochloride 25 mg — Green · round · 7 mmFull page in a later wave
GG44 Amitriptyline Hydrochloride 25 mg — Green · round · 6 mmFull page in a later wave
Discount cards: partner discount-card offers for this medicine will appear in this space once our partner programs launch. This slot is intentionally empty — we never link to places that sell prescription medicines.

Frequently asked questions

What pill has the imprint U 420?

A yellow round tablet with the imprint U 420 matches the FDA label for Amitriptyline Hydrochloride 25 mg. Always compare the colour, shape and size as well — short imprints are shared by different medicines — and confirm with a pharmacist.

What does the U 420 pill look like?

On its FDA label it is described as a yellow round tablet, 6 mm, with a score recorded as: no score.

How can I be sure this identification is right?

Check every characteristic — imprint (both sides), colour, shape, size and score — against the pill in your hand. If all of them agree, the pill matches the FDA label shown here, but that is still not a guarantee: counterfeit pills copy real imprints. A pharmacist can confirm the identification in person, and you should never take a pill you are not certain about.

Browse: all pills with imprint U 420 · Amitriptyline Hydrochloride — all forms & strengths · Yellow pills · Round pills

Source: FDA label data via DailyMed/openFDA · Label set ID c66e9088-4f34-4b97-971e-5272b45cfc97 · Record extracted from the openFDA bulk export of October 29, 2026. Spotted an error? Report it — include the imprint and what looks wrong.