Pill identification — FDA label match

I 21 Pill — Venlafaxine 75 mg (Orange, Round)

An orange round tablet with the imprint I 21 matches the FDA label for Venlafaxine 75 mg. Compare every detail below with your pill, and confirm with a pharmacist before relying on it.

ImprintI 21
Imprint partsI · 21 (the code is split across the pill — often one part per side)
Generic nameVenlafaxine
Active ingredient(s)Venlafaxine Hydrochloride 75 mg
Strength75 mg
Dosage formTablet
ColourOrange
ShapeRound
Size10 mm
ScoreTwo even pieces
LabelerRemedyrepack Inc.
NDC examples70518-2652-0, 70518-2652-1, 70518-2652-2, 70518-2652-3

What this medicine is

According to its FDA-approved label, Venlafaxine is described as follows (reference information only — not advice about whether it is right for anyone):

Venlafaxine tablets, USP are indicated for the treatment of major depressive disorder. The efficacy of venlafaxine tablets, USP in the treatment of major depressive disorder was established in 6-week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III or...

Equivalent pills — same medicine, different imprint

The pills below contain the same active ingredient at the same strength (Venlafaxine 75 mg). Different makers stamp their own codes, so equivalent pills often look completely different. This is factual label information — it is not a suggestion to substitute one product for another; only a pharmacist or prescriber can advise on that.

E 74 Venlafaxine 75 mg — Orange · capsule · 19 mmV 10 Venlafaxine 75 mg — Pink · capsule · 19 mmV75 Venlafaxine 75 mg — White · round · 8 mm1349 Venlafaxine 75 mg — White · round · 8 mm
395 Venlafaxine 75 mg — Pink · pentagon · 9 mmFull page in a later wave
ZA 36 75 MG Venlafaxine 75 mg — Orange · capsule · 20 mmFull page in a later wave
93 7385 93 7385 Venlafaxine 75 mg — Brown · capsule · 19 mmFull page in a later wave
EFFEXORXR 75 Venlafaxine 75 mg — Orange · capsule · 20 mmFull page in a later wave
HP 249 Venlafaxine 75 mg — Orange · oval · 4 mmFull page in a later wave
OS302 Venlafaxine 75 mg — White · round · 8 mmFull page in a later wave
W EFFEXORXR 75 Venlafaxine 75 mg — Orange · capsule · 20 mmFull page in a later wave
ZC 67 Venlafaxine 75 mg — Orange · round · 10 mmFull page in a later wave
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Frequently asked questions

What pill has the imprint I 21?

An orange round tablet with the imprint I 21 matches the FDA label for Venlafaxine 75 mg. Always compare the colour, shape and size as well — short imprints are shared by different medicines — and confirm with a pharmacist.

What does the I 21 pill look like?

On its FDA label it is described as an orange round tablet, 10 mm, with a score recorded as: two even pieces.

How can I be sure this identification is right?

Check every characteristic — imprint (both sides), colour, shape, size and score — against the pill in your hand. If all of them agree, the pill matches the FDA label shown here, but that is still not a guarantee: counterfeit pills copy real imprints. A pharmacist can confirm the identification in person, and you should never take a pill you are not certain about.

Browse: all pills with imprint I 21 · Venlafaxine — all forms & strengths · Orange pills · Round pills

Source: FDA label data via DailyMed/openFDA · Label set ID f56a0f70-bbb1-4e69-b969-965a72f0e2f0 · Record extracted from the openFDA bulk export of October 29, 2026. Spotted an error? Report it — include the imprint and what looks wrong.